Heisenberg.js

Not a framework, but a base project to help you structure your JavaScript code and files.
Makes use of the Mediator Pattern, so you can trigger events around your application.
Templating built in - Handlebars is included but feel free to change engines.
Follows the Object Literal Pattern with one global namespace, usually 'myApp' or 'chatApp'. In this case, it's 'breakingBad'.
Included: jQuery, Underscore.js and Handlebars.
A fully commented source to show you why it's doing what it's doing and how to build upon it's foundation.
The JavaScript version of the HTML5 Boilerplate.